Lot 95: RAMON Y CAJAL, Santiago (1852-1934). Histologie du systŠme nerveux de l'homme & des vert‚br‚s... dition fran‡ais revue & mise … jour par l'auteur. Translated by L. Azoulay. Paris: E. Arrault et Cie for A. Maloine, 1909-1911.

2 volumes, 8o (263 x 170mm). Half-titles, errata leaf for both volumes bound in at the end of volume II. Illustrations after Ram¢n y Cajal, some printed in red, blue, purple, and other colours. (Some spotting or browning, small hole affecting one line on I, 43/7.) Contemporary roan-backed, marbled-paper covered boards, the spine decorated and lettered in gilt (somewhat rubbed, short split on upper hinge of volume II, unobtrusive minor worming). FIRST FRENCH EDITION. THE DEFINITIVE EDITION OF RAM¢N Y CAJAL'S WORK, 'WHICH MUST RANK AS A CLASSIC OF MEDICAL HISTORY [... AND] CONTAINS THE CYTOLOGICAL AND HISTOLOGICAL FOUNDATIONS OF MODERN NEUROLOGY' (DSB, XI, p.274). Ram¢n y Cajal's contribution to neurology was remarkable; his studies and discoveries relating to the nervous system (particularly those of the years 1886 to 1906) 'may be said to have laid the histological foundations of our present knowledge of the nervous system' (DSB, loc. cit.), and in 1906 he was awarded the Nobel prize for physiology or medicine with Camillo Golgi. The present work was first published in Spanish under the title Textura del sistema nervioso del hombre y de los vertebrados (Madrid: 1899-1904), and brought together all of Ram¢n y Cajal's earlier researches, to produce a 'monumental work' (Garrison-Morton (1993) 1,293.1), which was then revised and augmented for the present, French edition. Ram¢n y Cajal explains the necessity of the revision in the 'Pr‚face de l'‚dition fran‡aise'; 'Depuis que la Textura del sistema nervioso del hombre y vertebrados a commenc‚ de paraŒtre, prŠs de douze ans se sont ‚coul‚s. Dans ce laps de temps, de nouvelles m‚thodes ont ‚t‚ cr‚‚es, dont les plus importants sont, sans contredit, les proc‚d‚s neurofibrillaires; de nombreux travaux ont ‚t‚ accomplis soit par l'auteur lui-mˆme, soit par ses collaborateurs [...], soit par les histologistes des autres pays; des th‚ories retentissantes ont surgi. Tout ce mouvement consid‚rable imposait … l'auteur l'obligation de revoir son oeuvre et de la corriger. De nombreux chapŒtres ont donc ‚t‚ remani‚s, entre autres ceux qui sont relatifs aux connexions intercellulaires, … la texture de la cellule nerveuse, … la structure des ganglions c‚r‚bro-spinaux, aux terminaisons p‚riph‚riques, … la neurog‚nŠse, … la structure de cervelet, etc.' (I, p.[xiii]). These revisions and additions produced a text which, compared to the Spanish original, was 'm s estimada por los especialistas en neurolog¡a' (Palau 247,478), and was the edition used for the facsimile published in 1952 by the Instituto Ram¢n y Cajal del Consejo Superior de Investigaciones Cient¡ficas. Palau 247,479; cf. Garrison-Morton (1993) 1,293.1 (Madrid: 1899-1904 edition). (2).